The Study of Bacteriophages in Antibiotic Research and Why They May be the Next Major Scientific Breakthrough

Bacteriophages, which are viral infections that reproduce to target and kill bacteria, were studied in Eastern Europe during the 1950’s by countries which did not have access to western medicine, including antibiotics. In 1 milliliter of sea water, billions of phages are present, with countless different varieties. Phages have tendril like appendages which are used to probe and identify hosts, clinging onto them, then forcing its own deoxyribonucleic acid down into the bacterial host. When this genetic code is introduced, it destroys the bacteria as a direct result. This leads to a chain reaction as hundreds more are produced each time this instance occurs, copies which then fledge out and find hosts of their own, building populations exponentially and wiping out bacterial infections completely. Bacteriophages were found prior to chemical antibiotics but when Penicillin was discovered, because it is so easy to develop and administer, chemical antibiotics became the clear path of choice in medicine with scientists not realizing the severity of this error until decades later. Antibiotics are often broad spectrum which is another reason antibiotic research overshadowed bacteriophagic research as different phages affect different bacteria and are therefore not broad spectrum. Because phages are self-replicating like bacteria, they have the ability to completely annihilate all bacteria presented before them in the same way that bacteria have the ability to totally annihilate their own host as well. Because of this, bacterial infections can be knocked out with 100% efficacy in all cases, regardless of the severity of the the infection, provided the correct phage is alotted enough time to do so. This is a task antibiotics often struggle to achieve and even if achieved, cannot be guaranteed in perpetuity as reinfection or resistance can occur at any time

The First Usage of Digital Animation (Computer Generated Imagery) Special Effects in Film

The first ever computer generated sequence in a movie occurred in Star Trek II: The Wrath of Khan which lasted for 60 seconds and is referred to as the “genesis scene”. The scene includes a retinal scan of Captain James Tiberius Kirk as well as a planet being hit by a missile which then creates a stable environment for life. Over 50 software programs were written to accomplish this task and the creators of the sequence went on to form the digital animation company Pixar

The Reason Aritifical Intelligence Differs From Traditional Software

Recently, many of the improvements made within the artificial intelligence sector have been due to the technology of “deep learning” which is also referred to as an “artificial neural network”. Traditional software is not intuitive as it simply follows a set of instructions predetermined by a programmer. If the software runs into a new problem which it has no answer prewritten for, it crashes. Deep learning is different as software can now write its own instructions instead of reading the instruction(s) of a programmer. Currently, as of 2021, deep learning is the equivalent of an all powerful, dim witted genie as it has the ability to evaluate the pixels of a photograph of a bottle of water, and can recognize with astonishing accuracy photographs of other water bottles, however it has no idea what the concept of water or the water bottle itself is, what the end user does to drink from the water bottle, what the end user needs the water for etc. This differs in human beings however as humans learn from a sample size of one, and are able to surmise the purpose of water and everything else which is relevant from witnessing it being used upon a single occasion

Rapid Advancements Within Computer Technologies Allowing for the Reduction of Cost and Increase of Performance

In 1985, the worlds most powerful computer was the Cray-2 which cost $35,000,000 ($35 million), and could not see, hear, or speak with its environment. Today, smartphones process data 10x faster and cost less than $1000.00, with the ability to see, hear, and interact with the end user (e.g Apple’s Siri, Microsoft’s Cortana, Samsung’s Bixby etc.). In 1956, the International Business Machines Corporation’s best hard drive weighed 2000 lbs., was 5 megabytes in size, and cost $3000.00 per month which equates to $28,000 as of 2019 when accounting for inflation. In 2019, most solid state Universal Serial Bus drives possess 200x as much storage at a minimum and cost less than $5.00

Textile Pollution of the Citarum River in Indonesia

The Citarum River (pronounced “chit-ah-rum”) in Indonesia is considered to be the most heavily polluted river in the world with over 400 textile factories situated nearby which choose to dump their industrial waste directly into the river itself, treating the river as a sewer system which carries away waste. The problem is so intense that the Indonesian military has been implemented to help clean up the area but corporations have resorted to dumping their waste products at night and because the unseen chemicals are the real threat to those living near the river, these companies are permitted to continue dumping as no one can definitively prove their culpability without scientific measurements which are difficult to ascertain as Indonesia is a developing country with few resources. Corporations have even begun to strategically place their waste pipes under water so that they can pollute with impunity as no one can physically see the pollution being dumped. Water darker than its surroundings, steam, bubbles, and froth are all key signs which activists use to spot these illegal port systems. It’s difficult to pin point which factories produce textiles for western companies as western companies virtually always refuse to disclose which factories they work with. Some of the largest corporations in fashion (e.g. H&M, the Gap, Levi’s etc.) have revealed their sources but even with this disclosure, some of these companies have been linked to factories within this region. Indonesia isn’t a top 5 global producer of textiles, so to say that Indonesia is part of an even larger problem, is an accurate statement. Most people who live near the Citaum River use the river for bathing, drinking, and/or cooking, and noticeable dermatological effects have been noticed by those living within the area. The primary problem with the Citarum River is with heavy metals (e.g. mercury, cadmium, lead, arsenic etc.). Long term exposure to these substances can cause neurological problems as brain function becomes permanently damaged. These heavy metals are so dire that they can actually lower the intelligence quotient of children who are developing and attending their education. 28,000,000 (28 million) people rely upon the Citarum River daily and eat foods (e.g. rice) irrigated with its waters. Human rights activists have engaged these corporations by physically blocking piping and ducts which have caused the affected corporations to start hiring mercenary criminals to follow and attack those known to be a part of this resistance. Western consumers are the primary cause and possible solution for this problem because if there are no clients willing to purchase the garments, the industry as a whole will shift, not because of political pressure or governmental oversight, but rather because of sales. The problem is not centralized in Indonesia as other developing countries (e.g. India, Bangladesh, China etc.) are equally negatively impacted

China’s Influence Upon Foreign States and Their Associated Cultures

China has become highly adept at spreading its practices or at the very least, acquiring acceptance and tolerance of its practices, throughout the open markets of the world (e.g. American companies willing to do business with Chinese companies to access the Chinese marketplace despite the U.S. government experiencing continuous conflict with the Chinese government). Hollywood is perhaps the best example of this ideology taking shape. Hollywood’s business and by extension its profit model, is designed to produce blockbuster cinema for the box office, at regular intervals throughout each calendar year (e.g. for each holiday season etc.). China, due to its large population, has the worlds largest box office and as a direct result of this, in order to ascend to the level of becoming a major blockbuster film, movie studios are forced to capitulate and cooperate with the Chinese Communist Party. The Chinese government heavily censors cinema in China, however despite this, Hollywood movie production studios virtually always refuse to green light film scripts if they cannot be shown in China. This effectively means that the Chinese government has the ability to, and openly does, influence and shape the kinds of movies produced in the west simply by omission or refusal to accept a movie and its content. This means that in the future, China will become the cultural connoisseur and decision maker for the world, both in supply and demand of products and services (e.g. new films), solely due to the volume of the Chinese public and its appetite for western cinema

The Business Rationale Behind Videogame Pre-Order Perks

Videogame production companies focus heavily upon pre-order sales as these provide the best path to generating revenue, income which is then re-invested to make even more profit. Production studios spend a lot of time and effort trying to come up with appealing pre-purchase packages because the quicker income is generated, the quicker it can be re-invested, but perhaps as important, pre-sales are sold at the full retail price point unlike delayed sales which are often sold at a discounted rate. Video game production companies spend an immense amount of time developing demonstrations for conventions (e.g. E3, Comic Con, Blizzcon etc.) because this is considered the best opportunity to attract gamers and have them purchase on the spot. These demonstrations are often over the top and include features which won’t be in the final version set for release (e.g. advanced graphical shading features), akin to a bait and switch technique in which the best face is presented with the actual product which is less polished actually being delivered. This deception is intentional as it helps generate revenue which helps fuel the production of future gaming titles and franchises

The Fictional and Real Usage of Area Code “555” for Telephone Numbers

Not all phone numbers that begin with “555” are fictional. The phone number “555-1212” is one of the standard numbers for directory assistance throughout the United States of America and Canada and only “555-0100” through “555-0199” are specifically reserved for fictional use with the other numbers being reserved for actual assignment

The Traditional Sherpa’s of Mount Everest

The term “sherpa” is derived from the terms “shyar” (pronounced “shur”) which means “east” and “pa” which means “people” in Nepali. Migrants who populated the region around Mount Everest throughout antiquity came from the Tiber in the east, crossing the Nangpa La, which means “Elder’s Pass” in Nepali, to settle into Solukhumbu (pronounced “solo-koom-boo”), a region in which the minimum altitude is 4000 meters above sea level. Living a nomadic lifestyle is what made the sherpas expertise so desirable to British mountaineers who arrived a few centuries later. British mountain climbers realized the immense value that these expert travelers possessed which is how the relationship of domestic sherpas and foreign alpinists began. Sherpas were and continue to serve as porters and guides for foreign climbers and during the modern day, a sherpa trekking Mount Everest can expect to earn $6000.00 upon an expedition which intends to reach the summit

The Traditional Practice of the Japanese Geisha

Japanese geishas, referred to as “geiko” (pronounced “gay-ko”) first appeared 300 years ago during the Edo period, an era when Japan was closed to the rest of the world allowing its indigenous culture to flourish. There were once 80,000 geisha but that number has dropped to just 1000 during the modern day. It takes 5 long years to become a geisha, this time spent with no smartphone, no romantic relationships, and only 2 days off per month. Geishas undergo lessons in music and dance as well as tea making and etiquette. All food and lodging is provided by the geisha training institution so that students become completely and totally immersed within the geisha lifestyle. Geishas wear white masks of makeup as symbolism that what is concealed is more desirable than that which is revealed. Pink is painted onto the earlobes as a way to hide embarrassment from blushing, and bare skin is left in a “W” or “V” shape upon the back of the neck to accentuate the neck which is considered highly beautiful, sexual, and erotic in Japanese culture. Geishas are only supposed to entertain their client with highly cultured activities, and the profession is not supposed to be associated with sexual interaction