Category: Pharmacology

The Original Medical Term for an Intellectually Disabled Person and the Evolution of This Term

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The original medical term within psychology for a developmentally disabled person was “simpleton” during the 19th century which eventually became the wider used “moron”, from the Ancient Greek “moros” which means “dull”, a term originally considered neutral and non-pejorative. Because the term “moron” became used pejoratively within society by the 1960’s, the term was altered to become “retard”, from the Latin “retardare” which means “to make slow, delay, keep back, or hinder”. Because this term also became used pejoratively, the term was changed again in 2010 under the Barack Obama administration to become “intellectually disabled”. Other variants have become common place synonyms, often used interchangeably, either correctly or incorrectly, within society (eg. “developmentally delayed”, “specialized needs”, developmentally disabled” etc.)

The Naga Baba Holy Sadhus of India

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Naga babas who are naked holy men, reject the physical world including clothing to be closer to Lord Shiva, one of the most powerful gods in Hinduism. Naga babas live in the Himalayan mountains and smoke incredibly large amounts of cannabis regularly. Naga babas often hand out blessings for a small sum, carrying out the blessing by hitting the person requesting it on the head with a peacock feather wand

The Country Which Executes the Most Convicted Persons and the Method of Execution Used

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It is believed that China executes thousands of convicted persons each year, more than all other countries combined, as claimed by Amnesty International, due to the true value being closely guarded by the Chinese government. Typically Chinese executions are carried out with a single bullet to the back of the head/neck but intravenous poisons have also been used in recent decades

How Breath Alcohol Analysis Works

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Alcohol shows up in the breath because it gets absorbed from the mouth, throat, stomach and intestines into the bloodstream. Alcohol­ is not digested upon absorption, nor chemically changed in the bloodstream. As blood circulates through the lungs, some of the alcohol moves across the membranes of the lung’s alveoli, into the air stored within the lungs. Because the alcohol concentration in the breath is related to the concentration in the blood, an approximate measurement can be identified when using a simple ratio formula of breath alcohol to blood alcohol which is 2100:1. This means that 2100 milliliters of alveolar air will contain the same amount of alcohol as 1 milliliter of blood

The Fallacy of Transgender Female Athletes Competing at the Same Biological Level as Cisgender Female Athletes

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It is a common misconception that transgender athletes who transition from male to female have the same sexual dimorphisms and therefore the same athletic capabilities and baseline statistics as cisgendered women when competing within athletic competition. Cisgender males on average have 40% more upper body muscle/strength than cisgendered women and 30% more lower body muscle/strength than cisgendered women, although these are mere approximations which span the entire world population which is why this is not always the case. Female hormones can reduce these advantages by 5% – 10% within the human body of elite athletes, but it is at the current time, as of 2023, impossible to completely reverse the advantage of biological male puberty for transgender male to female athletes. Surprisingly, hormone therapy rapidly reduces hemoglobin levels to that of cisgender women however all other baseline statistics remain relatively the same post transition when using hormone replacement therapy. Even after 36 months of treatment, virtually all other baseline levels are higher than the average cisgender female. These discoveries suggest that physical strength may be preserved in transgender women during the first 3 years of hormone replacement therapy. It should be noted, if the athlete does not go through male puberty, these male hormone induced advantages do not apply. This is because these traits are largely associated with testosterone but not entirely

The Origin of the Use of Analgesia While Giving Birth

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Analgesia was not an option while giving birth until the mid 19th century as pain was believed to be a crucial part of the birthing experience. In 1591, Euphemia Maclean, a woman from Edinburgh, Scotland requested analgesia during the birth of her twins and was burned at the stake for this request. Analgesia started with Queen Victoria who used chloroform for the birth of her 8th child Leopold. It was Victoria’s experience that she told to others which made the practice catch on so quickly as Victoria felt that analgesia was an amazing invention which helped her immensely. In the 1950’s, the no medication approach swung back into fashion with Dr. Grantly Dick-Read, the first modern physician to suggest against analgesia as he believed the pain of childbirth to be psychological

Botulism Toxin (Botox) Disabling Portions of the Human Brain Related to Emotion

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Because human beings interpret emotions by mirroring one another, botulism toxin, more commonly referred to by the brand name “Botox”, when injected into the forehead, alters brain activity connected with various emotional states. The temporary paralysis of facial muscles from the use of Botox disables a person’s ability to mirror the person(s) they are interacting with. It also hinders their ability to read and interpret the facial expressions of others. Surprisingly, this information is being leveraged within studies of depression and patients diagnosed with borderline personality disorder, as it is believed that temporary paralysis of the forehead may help aid those who are experiencing clinical depression and/or a borderline personality disorder

Gender Reassignment Surgery: Male to Female

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The reason gender reassignment surgery is possible is because all human beings begin life with the same anatomy, with the ovaries starting from the gonadal ridge, becoming testicles if they drop and remaining as ovaries if they do not. In addition to this, the clitoris is effectively a short penis as both genitalia are physically and anatomically identical (e.g. nerve ending bundles, interior connection and placement, sexual function etc.). When male anatomy is transitioned into female anatomy, a reversal of embryology occurs. When a biological male transitions to become female, during surgery, the scrotal skin is excised after which it is opened to form the labia majora and labia minora, and part of it is utilized to line the new vaginal cavity. The testicles are removed in their entirety and the cliterous is formed using the head of the penis which allows the cliterous to function as it does upon the body of a biological female, with most patients able to orgasm post surgery once healed. The volume of erectile tissue is decreased as the penis is effectively folded over, but because the nerves and arteries remain attached, sensation remains. Once the cliterous is sutured into place, the vaginal tunnel is created which is the most difficult aspect of the entire surgical procedure. A space is created between the bladder and the rectum which is difficult as both structures contain significant blood supply and injury to these systems can cause major complications. A skin graft from the scrotum is then set in place onto a cylindrical mold and sutured around it once the cavity is produced so that it can be implanted. Hair follicles are obliterated as they will continue to grow internally if not removed which would cause further complications. The mold used is an approximation of the average male penis which allows surgeons to create a cavity large enough to allow for sexual intercourse if desired. Small cosmetic details are taken care of after which the patient is sutured and migrated out of the operating theater so that they can be left to rest and reawaken after the anesthesia administered wears off

How Methamphetamine Works Within the Human Brain

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Methamphetamine causes a rush of dopamine to be released which provides euphoria with a rapid onset. Typically the brain has a dopamine level of 50 – 75 units, but when methamphetamine is present within the system, this value bounds to become 900 – 1250 units, larger than any other drug. Over time, methamphetamine destroys the brain’s ability to produce dopamine naturally, allowing levels to fall below baseline, causing a person who uses the substance to crave more and more to feel normal and balanced. To provide a scale of reference, cocaine typically produces dopamine levels of 100 – 350 units

The Most Important Intervention to Avoid Suicide During a Mental Health Crisis

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In the U.S., most firearm related deaths are not homicides but rather suicides, and more people commit suicide by firearm then by all other methods combined. The timeframe of a suicidal crisis is typically 1 – 10 minutes in duration, and having a firearm at close reach increases the likelihood of a successful suicide attempt by 95%. If a firearm is not present during a moment of suicidal crisis, and another method is used to attempt suicide, this statistic plunges dramatically to become a 5% – 10% success rate. This is important as the means by which someone takes their life matters. Living in a firearm free home is a critically important aspect of suicide prevention for those who are at risk. It is recommended that during a crisis event, all firearms are unloaded and taken to a trusted friend, with all prescription, over the counter medications, and household poisons (eg. Draino etc.) locked away as well