The Test Subject and Scientific Experiment Which Proved the Fear Response in Human Beings Does Not Solely Reside Within the Amygdala

SM Amygdala MRIJustin Feinstein is one of the few scientists who have been able to study a woman who has zero fear response. To protect the woman’s identity, this subject is known only as “S.M.”, and Feinstein has had the opportunity to work with her under laboratory conditions and in real world scenarios (e.g. coffee meeting, sporting event, professional conference etc.) for the past 15 years as of 2018. S.M.’s lack of fear has had unexpected consequences within her life, as she displays no sense of typical fear induced scenarios (e.g. personal space, feeling completely comfortable being nose to nose with a complete stranger as the concept of personal space and discomfort has no meaning), heightened by the fact that S.M. does not produce typical signals of distrust when interacting with a novel person. S.M. lacks fear because she is without her amygdala, a physical trait observed in very few human beings, making S.M. one of the only people in the world to produce this physiology. S.M. has no amygdala because she has been diagnosed with Urbach-Wiethe Disease (pronounced “urr-bock vee-they”). The underlying etymology of Urbach-Wiethe Disease is still unknown but in patients with the condition, specific portions of the brain, in both hemispheres, can become subject to selective calcification which erodes the ability to function as designed. The amygdala acts as a sentry for potential fearful stimuli, and produces a response accordingly. The removal of or inability of the amygdala to work correctly results in a complete and total lack and/or loss of fear. This condition has caused S.M. considerable difficulty during her life as she has experienced dangerous interactions with those participating within the illicit drug trade. Upon one occasion, a stranger ran up to S.M., placed a firearm against her temple, and yelled “bang!”. Neighbors witnessed this event and notified law enforcement which puzzled S.M. as she did not view the event as dangerous or alarming and therefore did not expect to be contacted by the police. When the human body detects the intake of too much carbon dioxide, it can become pushed into a state of alarm. Feinstein wanted to better understand what would occur if he interfered with S.M.’s respiratory system, using 35% carbon dioxide during the first trial run. Feinstein found that S.M. was immediately fearful after a single intake breath, despite his original hypothesis of no fear response being observed. S.M. displayed an immediate and dramatic fear response with S.M. herself describing it as the “most intense fear ever felt” during her entire life. This single breath was revolutionary for neurology as it definitively proved that the amygdala is not the only region of the brain which controls and is related to fear

The Causation and Cure for Colorblindness

colorblind-examination

Being colorblind is more difficult than most people believe as those affected often cannot match clothing colors, tell when fruit is ripe, tell when meat is cooked, or tell when traffic lights are various colors in certain lighting conditions (e.g. flashing red being mistaken for flashing yellow). Color vision is trichromatic with 3 types of cone cells within the eyes which consist of blue, green, and red, which are sensitive to short, medium, and long wavelengths of light, with each cone permitting an observer to view approximately 100 different shades. When all shades are combined, the human eye can observe approximately 1,000,000 (1 million) different colors. Colorblindness can stem from faulty cone cells or an interruption between the pathway of the cones and the brain. Colorblindness has caused vehicular deaths due to accidents around the world which have occurred most often because a driver perceived a light as yellow when it was red in reality. Neuroscientist Professor Jay Neitz (pronounced “nites”), a color researcher at the University of Washington in the U.S. and his spouse, geneticist Maureen Neitz, have teamed up to try and cure colorblindness. Gene therapy is currently being researched around the world and scientists believe that colorblindness will be cured using gene therapy in the near future. Male squirrel monkeys are naturally red-green colorblind and gene studies have demonstrated that these monkeys can be afforded color vision after having a gene delivered into the cone cells within the eye. The gene produced transforms a subset of the green cones within the male squirrel monkeys eyes to force them to become red cones, red cones which have hijacked the squirrel monkeys neural circuitry which was previously utilized solely for blue-yellow color vision, essentially bifurcating into red-green cones and blue-yellow cones so that the monkeys examined developed full color vision like human beings as of 2019. The Neitz’s confirmed this by providing male squirrel monkeys colorblind examinations which when answered correctly, delivered a small treat of food after having undergone gene therapy. Trials in human beings have yet to start as the Neitz’s believe that this step is still a few years away, but expected to initiate during the 2020’s

The Link Between Dementia and Iron

Alzheimer's-Disease

Measuring iron in the brain is the best known way to confirm dementia without performing an autopsy after death. The brain naturally creates tiny bits of iron referred to as “magnetite”. As a human being ages, more and more iron accumulates within the brain. Too much iron however, is a hallmark of dementia. It is theorized that this overproduction of iron is actually due to external factors like pollution rather than naturally occurring phenomena. Dr. Barbara Marr, a world renowned expert and authority in respect to the measurement of metal in incredibly small particles, took thin tissue sections of affected brains obtained during autopsy and observed them under a highly resolved transmission electronmicroscope to review the particles within the neurons of the brain and found 2 different shapes of particle. The magnetite particles are beautifully crystalline, regular and geometric, whilst the opposing particles were rounded in shape, referred to as “spherls” or “nanospheres”, rounded in shape because they were originally molten droplets. For every 1 biologically manufactured magnetite, 100 artificially implanted foreign particles of iron are found within the brains of those affected by this condition as confirmed by a study which took place in Mexico City, Mexico. Although not definitely proven, the shape of these secondary particles is remarkably similar to that of airborne pollution, which suggests to scientists that there is a discernible correlation between the 2 types

The Evolution of Primitive and Sophisticated Neural Networks

neural-network

The human brain has 100,000,000,000,000 (100 trillion) connections and 86,000,000,000 (86 billion) neurons, which is more connections and neurons than there are stars in the Milky Way Galaxy. Ironically, the majority of the most successful creatures on Earth do not have a brain; organisms like plants, coral, and jellyfish. The sea squirt is a primary example as it has just 200 neurons, allowing it only to perceive and display simple interaction with the environment by sensing light and moving its flagellum. The sea squirt moves around until it finds a rock, then it dumps its tail and uses those once dedicated neurons for different applications, staying anchored to this spot for the rest of its life. Neurons were originally designed to allow for simple motion and movement, but as evolution progressed steadily, neural networks began to build and design intelligent life which is capable of consciousness and a sense of self but also more abstract concepts like art, mathematics, and science

The Purpose and Setup of Sensory Deprivation Tanks

sensory-deprevation-tankSensory deprivation involves a large tank which is filled up with water heated to 37 degrees Celsius, the same temperature as the body, and 1000 lbs., or some variation of this in smaller tanks, of Epsom salts are added, so that half of the body is underwater and half of it is above because of the density of the salt within the water. Human beings have low fat content on average and need this salt otherwise a participant would sink. An observer cannot distinguish between water and air because when within the tank as it feels the same, and after a short period of time, because there are no visual queues being that the tank is completely dark, in the absence of sensory input, an observer typically begins to think differently as the brain has more resources dedicated to thought as less surface area is compartmentalized for sensory stimuli. This process is extremely similar to meditation, however meditation takes both time and practice to achieve upon a consistent, reliable, and meaningful level, as opposed to a sensory deprivation tank in which reaching such a state is essentially automatic provided enough time passes within the tank for the observer. This experience ends instantaneously once the tanks door is opened however, unlike meditation or the use of pharmacological agents to achieve a psychedelic or intrinsic experience

The Danger of Air Pollution Gaining Access to the Brain

air-pollution

The reason pollution has a metallic taste and scent and that it burns the eyes when exposed to it is because the particles of air pollution are tiny enough that they can travel through nerve cells, and gain direct entry to the brain, where the olfactory bulbar meets the frontal cortex, as there is no blood-brain barrier at this point. The body protects itself through the blood-brain barrier, which means that particles within the bloodstream, cannot get directly into the brain. This system has a slight flaw however as the nose acts as a direct conduit for incredibly tiny particles to bypass this security mechanism

The Scientific Study of Consciousness After Decapitation In Rodents

laboratory-rat

Brainwave activity in laboratory rats has been measured after decapitation. Scientists have determined that the brain stays conscious for 4 seconds after decapitation. Laboratory rat brain cells could theoretically start working again if intervention is quick enough supplying the brain with adequate oxygen and glucose

Possible Future Technologies Which May Be Used In a Judicial Capacity

brain-electroencephalogram

Subjects who display increased alpha wave activity, specifically within the temporal region of the brain when being scanned with electroencephalograph imaging is typically indicative of a person recalling a memory. Subjects who display increased alpha wave activity within the frontal region of the brain when being scanned with that same imaging technology is indicative of a person fabricating or conceptualizing a story. These types of scans may be used in the future within the criminal justice system when determining whether or not a person is telling the truth or fabricating an alternate summary of events

The Effects of Hydrocephalus

hydrocephalus

Hydrocephalus affects over 500,000 children worldwide. Hydrocephalus can be caused by infection, genetic anomalies, or head injuries. The reason hydrocephalus causes the heads of infants to grow so incredibly large is because all babies are born with soft, mailable skulls which are capable of expanding over 3x its typical size within the first 12 – 18 months after birth. Hydrocephalus is caused because the valve located between the left and right brain hemispheres which drains cerebrospinal fluid down the spine and into the abdomen, becomes blocked. When medical examinations are available, hydrocephalus can be diagnosed in utero allowing for immediate intervention. When the severity of hydrocephalus is diagnosed via computed tomography scan, the brain does not show up, as the water present takes up so much volume that the cavity where the brain would normally be, shows up as black, as water obstructs the ability of the scanner to take a complete image. The most common intervention of hydrocephalus is the installation of a shunt, but shunts have an 80% failure rate causing future uncertainty for those who have experienced hydrocephalus. Uganda has an unusually high occurrence rate of hydrocephalus primarily due to high rates of infant infection and lack of medical facilities and care

Albert Einstein’s Autopsy

Albert-Einstein

Albert Einstein died of heart failure at the age of 76. Thomas Harvey, the pathologist who performed Einstein’s autopsy removed and held onto Einstein’s brain without telling his superiors, colleagues, or Einstein’s next of kin. When Einstein’s family found out about this event via media news coverage which stated that Einstein’s head was concave during cremation, they were understandably outraged. Harvey sold Einstein’s family upon the idea of allowing him to study Einstein’s brain under the conditions that Harvey never make a profit from doing so, nor use it to garner personal fame. Einstein stated prior to his death that he wished to be cremated as he did not want people visiting his gravesite in reverence or worship of his brilliance. Harvey was not a neurologist by specialty and because of this he had a friend who was a neurosurgeon help him slice Einstein’s brain into 240 cubes and then created at least 12 sets each containing 200 microscopic slides. Harvey was hoping that top researchers from around the world would voluntarily analyze segments of Einstein’s brain to collectively come up with a reason for his brilliance but to his surprise he found that no one wanted to be associated with the project or Harvey himself