Tag: testosterone

The Caribbean Village of Biological Males Born Without Male Genitalia

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There is a village in the Dominican Republic called Salinas, in which 1 in 90 of the people born are born as males, with testicles, but without a penis, because of misconstrued instructions at birth. In males, the gene on the Y chromosome, specifically the Sex Determining Region Y (SRY), instructs the gonads to become testicles. This leads to the creation of dihydrotestosterone which is a stronger version of testosterone. Dihydrotestosterone transforms the tubercle which all males and females have, into a penis. Females do not make dihydrotestosterone, therefore their gonads become ovaries, and the tubercle becomes a clitoris. Infants perceived as female at birth, due to a lack of dihydrotestosterone during fetal development, later develop a penis during puberty when testosterone triggers penile growth, as it does in typical male development. Those who lack the ability to create dihydrotestosterone, as is the case with those born as males but raised as females in the Caribbean village of Salinas, Dominican Republic where it is common, are technically male, but without a penis, a condition referred to as “5 alpha reductase deficiency”. This condition is quite well accepted in this part of the world and even has a term which is “guevedoce(s)”, (pronounced “guava-doh-chey”) which means “penis/testicles at 12” in Spanish. This condition whilst common in this region of the Caribbean, it is very rare in other parts of the world

The Fallacy of Transgender Female Athletes Competing at the Same Biological Level as Cisgender Female Athletes

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It is a common misconception that transgender athletes who transition from male to female have the same sexual dimorphisms and therefore the same athletic capabilities and baseline statistics as cisgendered women when competing within athletic competition. Cisgender males on average have 40% more upper body muscle/strength than cisgendered women and 30% more lower body muscle/strength than cisgendered women, although these are mere approximations which span the entire world population which is why this is not always the case. Female hormones can reduce these advantages by 5% – 10% within the body of elite athletes, but it is at the current time, as of 2023, impossible to completely reverse the advantage of biological male puberty for transgender male to female athletes. Surprisingly, hormone therapy rapidly reduces hemoglobin levels to that of cisgender women however all other baseline statistics remain relatively the same post transition when using hormone replacement therapy. Even after 36 months of treatment, virtually all other baseline levels are higher than the average cisgender female. These discoveries suggest that physical strength may be preserved in transgender women during the first 3 years of hormone replacement therapy. It should be noted, if the athlete does not go through male puberty, these male hormone induced advantages do not apply. This is because these traits are largely associated with testosterone but not entirely