Category: Epidemiology

The Development of Lock Hospitals Within England for Female Sex Workers During the 19th Century

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Due to the fact that sexually transmitted infections and diseases were rampant among English soldiers, in 1864 novel legislation entitled the Contagious Diseases Act was passed which permitted any woman suspected of prostitution as young as 13 years of age, to be forcibly examined by a physician. Institutions referred to as “lock hospitals” were established and setup so that women suspected of spreading disease could be detained and examined, and if they were positive in their evaluation, they could then be incarcerated for up to 3 months. It never occurred however to the English government that men could also spread sexually transmitted infections and diseases which is why men were immune from this legislation and a key reason as to why the problem was never resolved. Because of this, in 1886, this legislation was repealed

The Toxicity of Tanneries During the French Revolution

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One of the largest contributors to pollution during the French Revolution was the work of tanneries, which converted what is essentially animal skin, into leather goods. First the hide was immersed in an alkaline lime and water solution for up to 3 weeks, then it was brought out and shaved for both the hair on one side of the hide and the dissolved fat referred to as “sinew” on the other side. Once this process had been complete, dog and bird feces were mixed with hot water and human urine to create a bacterial cocktail which would work together to soften the hide and help it absorb dye. All of these components were dumped into local water sources once they had served their purpose which made living around them nearly impossible, with many people developing ulcerative lesions upon their throats when around these ingredients for extended periods of time

The Correlation Between Cats and the Bubonic Plague of Europe

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During the Middle Ages and up until the Salem Witch Trials, cats were killed alongside their owners who were believed to be practicing the dark arts of magic, sorcery, and witchcraft. Typically cats were burned alive in ceremonial bonfires. Ironically, had this not occurred, the Bubonic Plague probably wouldn’t have been as prolific as it was as the fleas found upon the rats who carried the disease, would have been killed alongside their host by the very cats which were killed in droves by human beings. Cats are partially resistant to the Bubonic Plague but with few to keep the rat population in check, the plague was able to wash over Europe and kill 25,000,000 (25 million) people which was 25% of the European population

How the Rabies Virus Pathogen Infects and Propagates Within Mammalian Hosts

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The rabies virus causes hostility within its host because aggressive behavior (e.g. biting etc.) is crucial for the transmission of the pathogen due to the fact that the virus is primarily secreted within the saliva of its hosts, although it can be present within and therefore transmitted via other tissues as well (e.g. infected brain tissue coming into contact with the open wound of a host etc.). The rabies virus primarily affects the central nervous system of its host, involving both the brain and spinal cord, causing inflammation of the brain referred to as “encephalitis”, and triggering various other neurological symptoms which help aide propogation (e.g. aggression, confusion, hallucinations etc.). The rabies virus travels along nerves from the wound site of the infection to the brain, where it then replicates and causes inflammation. Once the rabies virus reaches the brain, it can spread rapidly throughout the body via the central nervous system, leading to severe neurological symptoms and death in 100% of cases if left untreated

The Importance of Gastrointestinal Microbes for Weight Loss

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There are 100,000,000,000,000 (100 trillion) microbes within the gastrointestinal system and scientists have learned that by transplanting microbes from one animal to another, weight gain and weight loss can be turned on and off at will. Scientists now understand that the greater diversity a person has in terms of the types of microbial life which live within their body, the less likely they are to gain weight or maintain a higher than ideal body weight, with the exact opposite effect occurring in those who have lower than average values in reference to the number of microbes living within the body. Diets rich in fiber are typically associated with higher values of microbes, so increasing fiber intake, can significantly reduce overall body weight and promote the existence and health of many different kinds of microbes. Increasing fiber content for only a few days, has a measurable and marked effect upon microbrial gastrointestinal health

The Generational Health Effects of Smoking During Pregnancy

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Smoking during pregnancy doubles the risk of Attention Deficit Hyperactivity Disorder in children. Exposure to cigarette smoke during pregnancy can persist transgenerationally, being passed from parent to child, and can result within a higher probability of Attention Deficit Hyperactivity Disorder in 2nd and 3rd generation offspring. Smoking was purported as a remedy for morning sickness during the 1930’s which could explain why Attention Deficit Hyperactivity Disorder has been identified more and more throughout the past few decades. It takes a person with Attention Deficit Hyperactivity Disorder 150 milliseconds longer than a person without, to react to stimuli, which is the equivalent difference between a successful hit and a near miss of a ball with a baseball bat

The Reasons Public Bathroom Stalls Do Not Touch the Ground

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The reason commercial and industrial buildings have bathroom stalls which do not reach the floor is multifaceted. The design of doors which do not touch the ground provides a myriad of benefits including being easier to clean for custodial staff (e.g. reaching all areas with mop and bucket or pressure washer etc.), providing emergency access for first responders (e.g. elderly person who is unfamiliar and becomes confused thus falling down, an unconscious person who has suffered a health issue, wanted person hiding from law enforcement etc.), acting as a deterrent for unintended uses (e.g. using illicit drugs, consuming alcohol underage, sexual intercourse etc.), providing better air circulation between stalls so that odors do not linger, and limiting the spread of bacteria which reside upon the floor. In addition to these main reasons, it is additionally more cost effective as less material is used and the same door size fits and can be used for virtually all establishments, it is easier to escape from if a lock jams occurs, and toilet paper can be shared between stalls

The Discovery of Bacterium Causing Stomach Ulcers

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For decades the medical community believed gastric ulcers were directly related to stress with the only options for relief being antacids and surgery. In the early 1980’s, Australian physicians Barry Marshall and Robin Warren discovered through biopsies of gastric ulcers, that nearly all were overrun by helicobacter pylori bacteria. Helicobacter pylori only seems to infect humans, as studies performed upon pigs and rats were unsuccessful as these animals were unable to contract the bacterium. Marshall decided to infect himself and within 5 days of doing so, he started running to the bathroom each morning to throw up. Tests demonstrated that Marshall had gastritis, a precursor to an ulcer. Marshall took antibiotics and was cured, proving once and for all that ulcers are caused by bacteria not stress. In 2005, Marshall and Warren won the Nobel Prize in Medicine for their findings

The First U.S. Presidential Vaccine Mandate

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U.S. President George Washington issued the first presidential vaccine mandate, requiring all soldiers within the continental army to become vaccinated against smallpox on February 5, 1777. 90% of deaths during the American Revolution were due to disease, with smallpox being the most prevalent and difficult pathogen for the military to control. Immunization was viewed as an achievable solution to a virtually insurmountable problem as death from smallpox plunged from 30% to 2% after a becomming immunized. Vaccination, or “variolation” as it was referred to during the era, was achieved by taking a small piece of an active smallpox sore from an infected person, and then introducing it to the person being inoculated via inhalation or by scratching their arm and introducing the virus by touch. The mandate, although initially detested, became highly successful in its pursuit of lowering soldier mortality rate, with 40,000 soldiers vaccinated by the end of 1777

The Study of Bacteriophages in Antibiotic Research and Why They May be the Next Major Scientific Breakthrough

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Bacteriophages, which are viral infections that reproduce to target and kill bacteria, were studied in Eastern Europe during the 1950’s by countries which did not have access to western medicine, including antibiotics. In 1 milliliter of sea water, billions of phages are present, with countless different varieties. Phages have tendril like appendages which are used to probe and identify hosts, clinging onto them, then forcing its own deoxyribonucleic acid down into the bacterial host. When this genetic code is introduced, it destroys the bacteria as a direct result. This leads to a chain reaction as hundreds more are produced each time this instance occurs, copies which then fledge out and find hosts of their own, building populations exponentially and wiping out bacterial infections completely. Bacteriophages were found prior to chemical antibiotics but when Penicillin was discovered, because it is so easy to develop and administer, chemical antibiotics became the clear path of choice in medicine with scientists not realizing the severity of this error until decades later. Antibiotics are often broad spectrum which is another reason antibiotic research overshadowed bacteriophagic research as different phages affect different bacteria and are therefore not broad spectrum. Because phages are self-replicating like bacteria, they have the ability to completely annihilate all bacteria presented before them in the same way that bacteria have the ability to totally annihilate their own host as well. Because of this, bacterial infections can be knocked out with 100% efficacy in all cases, regardless of the severity of the the infection, provided the correct phage is alotted enough time to do so. This is a task antibiotics often struggle to achieve and even if achieved, cannot be guaranteed in perpetuity as reinfection or resistance can occur at any time